Patrice Decker Selected Research

Nucleosomes (Nucleosome)

1/2021	Deoxyribonuclease 1-Mediated Clearance of Circulating Chromatin Prevents From Immune Cell Activation and Pro-inflammatory Cytokine Production, a Phenomenon Amplified by Low Trap1 Activity: Consequences for Systemic Lupus Erythematosus.
3/2011	Nucleosome-induced neutrophil activation occurs independently of TLR9 and endosomal acidification: implications for systemic lupus erythematosus.
5/2009	Nph, DC and chromatin-mediated pathogenesis in systemic lupus erythematosus.
6/2007	Circulating nucleosomes due to a defective clearance of dying cells: consequences for systemic lupus erythematosus.
12/2006	TLR2/TLR4-independent neutrophil activation and recruitment upon endocytosis of nucleosomes reveals a new pathway of innate immunity in systemic lupus erythematosus.
4/2006	Nucleosome autoantibodies.
3/2005	Nucleosome, the main autoantigen in systemic lupus erythematosus, induces direct dendritic cell activation via a MyD88-independent pathway: consequences on inflammation.
7/2003	Nucleosomes induce lymphocyte necrosis.

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Patrice Decker Research Topics

Disease

11	Systemic Lupus Erythematosus (Libman-Sacks Disease) 01/2021 - 07/2003
6	Inflammation (Inflammations) 01/2020 - 07/2003
6	Rheumatoid Arthritis 01/2020 - 01/2016
4	Autoimmune Diseases (Autoimmune Disease) 01/2021 - 01/2019
3	Neoplasms (Cancer) 01/2021 - 12/2004
3	Arthritis (Polyarthritis) 01/2020 - 01/2016
2	Sepsis (Septicemia) 01/2021 - 01/2019
2	Infections 01/2020 - 01/2017
2	Experimental Arthritis 01/2017 - 01/2016
1	Hypersensitivity (Allergy) 01/2020
1	Genetic Predisposition to Disease (Genetic Predisposition) 01/2020
1	Granuloma 01/2017
1	Bacterial Infections (Bacterial Infection) 01/2017
1	Tuberculosis (Tuberculoses) 01/2017
1	Connective Tissue Diseases (Connective Tissue Disease) 04/2006
1	Necrosis 07/2003

Drug/Important Bio-Agent (IBA)

8	Nucleosomes (Nucleosome)IBA 01/2021 - 07/2003
5	AutoantigensIBA 03/2011 - 07/2003
3	ChromatinIBA 01/2021 - 05/2009
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2020 - 01/2017
2	EpitopesIBA 01/2020 - 12/2004
2	Chemotactic FactorsIBA 12/2006 - 03/2005
2	Interleukin-8 (Interleukin 8)IBA 12/2006 - 03/2005
1	MHC class I-related chain AIBA 01/2021
1	Deoxyribonucleases (DNase)FDA Link 01/2021
1	micaIBA 01/2021
1	CytokinesIBA 01/2021
1	Type II Tumor Necrosis Factor ReceptorsIBA 01/2020
1	Imiquimod (Aldara)FDA LinkGeneric 01/2020
1	SaltsIBA 01/2020
1	Anti-Citrullinated Protein AntibodiesIBA 01/2019
1	VaccinesIBA 01/2017
1	Etanercept (Enbrel)FDA Link 01/2017
1	Janus Kinase InhibitorsIBA 12/2016
1	Interleukin-33IBA 01/2016
1	InterferonsIBA 07/2011
1	Complement System Proteins (Complement)IBA 05/2009
1	AutoantibodiesIBA 04/2006
1	Peptides (Polypeptides)IBA 12/2004
1	Cyclin D1IBA 12/2004
1	Endopeptidase K (Proteinase K)IBA 07/2003
1	Deoxyribonuclease I (Nickase)IBA 07/2003
1	Monoclonal AntibodiesIBA 07/2003

Therapy/Procedure

1	Injections 01/2016
1	Immunotherapy 12/2004